What is the minimum order quantity for calcium thioglycolate?

The minimum order quantity for calcium thioglycolate from DepiStudio is 1kg. Bulk pricing is available from 25kg, with custom pricing for 100kg and above. All orders ship with COA and MSDS documentation.

What is calcium thioglycolate used for in cosmetics?

Calcium thioglycolate is primarily used as the active ingredient in depilatory (hair removal) creams. It breaks disulfide bonds in the keratin protein structure of hair, causing the hair shaft to weaken and dissolve at or near the skin surface. It is also used in hair waving and straightening preparations. Under EU Regulation No. 1223/2009, it is permitted in depilatory products at concentrations up to 5% (as thioglycolic acid).

What is the difference between calcium thioglycolate, sodium thioglycolate, and potassium thioglycolate?

All three are salts of thioglycolic acid and share the same mechanism of action (disulfide bond cleavage in keratin). Calcium thioglycolate (CAS 814-71-1) offers a more stable pH profile in formulations and is the most commonly used salt in modern depilatory cream formulations. Sodium thioglycolate (CAS 367-51-1) is used in hair waving products. Potassium thioglycolate (CAS 34452-51-2) is less common commercially but used in some professional applications. Ammonium thioglycolate is the dominant salt in cold wave/perm preparations.

Raw Material · CAS 814-71-1

Calcium Thioglycolate — Cosmetic Grade, Factory Direct

Q: What is the CAS number for calcium thioglycolate?

The CAS number for calcium thioglycolate is 814-71-1. It may also be referenced under CAS 65208-41-5 (trihydrate form) or CAS 29820-13-1 in some databases.

Manufactured in-house by Guangzhou Daile Biotechnology. Supplied as white crystalline powder with full batch documentation. MOQ 1kg. Volume pricing from 25kg.

Request a Quote → Download COA / MSDS

TECHNICAL DATA SHEETDS-CT-2026

Calcium Thioglycolate

CAS Number814-71-1

INCI NameCalcium Thioglycolate

Molecular FormulaC₄H₆CaO₄S₂

Molecular Weight214.26 g/mol

AppearanceWhite to off-white powder

Purity (Assay)≥ 98%

MOQ1kg

Packaging25kg fibre drum

CAS 814-71-1 COA + MSDS Included MOQ 1kg REACH Referenced Factory Direct

Technical Specifications

Full Technical Data Sheet

All parameters below reflect our standard cosmetic-grade product. Batch-specific values are confirmed in the Certificate of Analysis (COA) shipped with each order.

CALCIUM THIOGLYCOLATE · COSMETIC GRADE CAS 814-71-1

IDENTIFICATION

CAS Number

814-71-1

INCI Name

Calcium Thioglycolate

Systematic Name

Calcium 2-mercaptoacetate

Molecular Formula

C₄H₆CaO₄S₂

Molecular Weight

214.26 g/mol

Related CAS (Trihydrate)

65208-41-5 / 29820-13-1

PHYSICAL & CHEMICAL PROPERTIES

Appearance

White to off-white crystalline powder

Odour

Slight characteristic sulfurous odour

Solubility

Soluble in water; slightly soluble in ethanol

pH (1% aqueous solution)

6.0 – 8.0

Purity (Assay)

≥ 98%

Loss on Drying

≤ 1.0%

Heavy Metals

≤ 20 ppm

Storage

Cool, dry, sealed. Away from oxidising agents. 15–25°C.

SUPPLY INFORMATION

MOQ

1kg

Standard Packaging

25kg fibre drum (inner PE bag)

Small Quantity Pack

1kg / 5kg aluminium foil bag

Shipping Terms

EXW Guangzhou · International freight quoted separately

Lead Time

3–5 days (stock) · 7–14 days (custom batch)

Documentation

COA · MSDS · REACH ref. available

Not sure what affects the final price? See our Calcium Thioglycolate Price Guide for a full breakdown of what drives cost per kg.

Request a Quote → Download Sample COA / MSDS

Applications

Where Calcium Thioglycolate Is Used

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Depilatory Creams & Gels

Primary active ingredient in hair removal creams. EU Regulation No. 1223/2009 permits use in rinse-off depilatory products at up to 5% (expressed as thioglycolic acid). Works by breaking disulfide bonds in hair keratin.

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Hair Waving Preparations

Used in cold wave and hair straightening formulations as an alternative thioglycolate salt. The calcium form offers a milder pH profile compared to ammonium thioglycolate in some hair waving applications.

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R&D / Formulation Research

Supplied to cosmetic formulators and research laboratories in 1kg and 5kg quantities for prototype development, stability testing, and comparative studies with other thioglycolate salts.

Formulator’s Reference

Calcium vs. Sodium vs. Potassium vs. Ammonium Thioglycolate

All four are salts of thioglycolic acid with the same mechanism of action. The choice between them depends on formulation pH target, application type, and regulatory context.

Property	Calcium CAS 814-71-1	Sodium CAS 367-51-1	Potassium CAS 34452-51-2	Ammonium CAS 5421-46-5
Primary use	Depilatory cream	Hair waving	Specialty cosmetic	Cold wave / perm
pH stability	High	Medium	Medium	Lower
Odour intensity	Low–Mild	Mild	Mild	Strong
EU Reg. 1223/2009	✓ Permitted	✓ Permitted	✓ Permitted	✓ Permitted
Available from us	✓ In stock	✕	✕	✕

Note: pH stability and odour ratings are general characterisations for formulation guidance purposes. Actual values depend on formulation concentration, pH, and excipient composition.

For a deeper breakdown of how these salts differ in formulation performance, see our full comparison: Calcium vs Sodium vs Potassium Thioglycolate. If you’re researching cold wave / perm applications specifically, see Thioglycolate Salts in Perm Lotions, Explained.

FAQ

Sourcing Questions

What is the CAS number for calcium thioglycolate?

The CAS number for anhydrous calcium thioglycolate is 814-71-1. The trihydrate form may appear under CAS 65208-41-5 or 29820-13-1 in some databases. Our standard product is the anhydrous form, CAS 814-71-1.

Do you supply REACH-registered calcium thioglycolate?

We can provide REACH reference documentation for EU buyers. As a Chinese manufacturer exporting to the EU, the importer or their Only Representative (OR) is responsible for REACH registration obligations. We provide the substance identification and SDS documentation needed to support this process.

Can I request a sample before placing a bulk order?

Yes. The MOQ is 1kg, which also serves as our sample quantity for raw material buyers. A 1kg sample order ships with a full COA and MSDS. Request a quote for pricing and shipping costs to your location.

What packaging is used for bulk shipments?

Standard bulk packaging is 25kg fibre drums with inner polyethylene (PE) bag to prevent moisture ingress. Small quantities (1kg, 5kg) are packed in sealed aluminium foil bags. Custom packaging available on request for larger orders.

Calcium Thioglycolate — Cosmetic Grade, Factory Direct

Calcium Thioglycolate

Full Technical Data Sheet

Where Calcium Thioglycolate Is Used

Depilatory Creams & Gels

Hair Waving Preparations

R&D / Formulation Research

Calcium vs. Sodium vs. Potassium vs. Ammonium Thioglycolate

Sourcing Questions

Ready to Source Calcium Thioglycolate?